The trial was carried out by an international group of researchers – including a team from Case Western Reserve University (CWRU) in Cleveland, OH – and is reported in the journal Clinical Infectious Diseases.
The investigators found – contrary to previous studies – that the commonly used herpes drug valacyclovir (known under the brand name Valtrex) reduced levels of HIV-1 even in patients that did not have herpes.
HIV-1 is the predominant strain of human immunodeficiency virus (HIV) that causes acquired immune deficiency syndrome (AIDS). When people refer to HIV without saying which type of virus, they usually mean HIV-1.
Previously it was thought that the herpes simplex virus 2 (HSV-2) had to be present for valacyclovir to be effective against HIV.
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